Vidya Gopalakrishnan Selected Research

RE1-silencing transcription factor

1/2021	REST promotes ETS1-dependent vascular growth in medulloblastoma.
1/2019	Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma.
1/2018	Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration.
8/2012	REST is a novel prognostic factor and therapeutic target for medulloblastoma.

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Vidya Gopalakrishnan Research Topics

Disease

32	Neoplasms (Cancer) 01/2022 - 07/2006
9	Medulloblastoma 01/2021 - 01/2007
4	Glioma (Gliomas) 01/2020 - 07/2006
4	Brain Neoplasms (Brain Tumor) 12/2017 - 03/2006
3	Breast Neoplasms (Breast Cancer) 11/2020 - 10/2019
3	Neuroblastoma 10/2017 - 10/2010
2	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 11/2007
2	Osteosarcoma (Osteogenic Sarcoma) 01/2021 - 01/2019
2	Lymphoma (Lymphomas) 01/2020 - 01/2019
2	Diffuse Intrinsic Pontine Glioma 01/2020 - 01/2018
1	Carcinogenesis 11/2020
1	Drug-Related Side Effects and Adverse Reactions 09/2020
1	Body Weight (Weight, Body) 01/2020
1	Ependymoma 01/2020
1	Adenocarcinoma 01/2020
1	Ovarian Neoplasms (Ovarian Cancer) 10/2019
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Hematologic Neoplasms (Hematological Malignancy) 12/2017
1	Carcinoma (Carcinomatosis) 10/2017
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2016
1	Genomic Instability 11/2013
1	Chromosome Fragility 09/2012

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 11/2020 - 11/2011
4	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 03/2006
4	RE1-silencing transcription factorIBA 01/2021 - 08/2012
4	Etoposide (VP 16)FDA LinkGeneric 10/2010 - 07/2006
3	disaribIBA 01/2020 - 01/2016
3	ChromatinIBA 01/2019 - 10/2010
3	Pharmaceutical PreparationsIBA 01/2019 - 07/2006
3	Valproic Acid (Depakote)FDA LinkGeneric 10/2010 - 11/2007
2	MethyltransferasesIBA 11/2020 - 01/2018
2	CurcuminIBA 09/2020 - 10/2019
2	dipinacoline glutamateIBA 01/2020 - 01/2018
2	Lysine (L-Lysine)FDA Link 01/2020 - 01/2018
2	Phosphotransferases (Kinase)IBA 01/2019 - 10/2017
2	Histones (Histone)IBA 01/2017 - 07/2009
2	Methotrexate (Mexate)FDA LinkGeneric 10/2015 - 02/2009
2	ThiadiazolesIBA 10/2014 - 09/2014
2	Type II DNA Topoisomerases (Topoisomerase II)IBA 10/2010 - 11/2007
2	Histone Deacetylase InhibitorsIBA 11/2007 - 01/2007
1	Neurofibromin 1 (Neurofibromin)IBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	bempegaldesleukinIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Interleukin-2 (IL2)IBA 01/2021
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	licochalcone AIBA 11/2020
1	Arginine (L-Arginine)FDA Link 11/2020
1	Alanine Transaminase (SGPT)IBA 09/2020
1	NitrogenIBA 09/2020
1	Metalloproteases (Metalloproteinases)IBA 09/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 09/2020
1	Antineoplastic Agents (Antineoplastics)IBA 09/2020
1	Urea (Carbamide)FDA LinkGeneric 09/2020
1	Trypan Blue FDA Link 10/2019
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 10/2019
1	FluorineIBA 05/2019
1	adavosertibIBA 01/2019
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2019
1	Gemcitabine FDA Link 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	VimentinIBA 01/2019
1	Oncogene Proteins (Oncogene Protein)IBA 01/2019
1	CyclinsIBA 01/2019
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2019
1	CateninsIBA 01/2019
1	Ligases (Synthetase)IBA 11/2018
1	histone H3 trimethyl Lys4IBA 01/2018
1	EnzymesIBA 01/2018
1	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2017
1	carfilzomibIBA 12/2017
1	Biological ProductsIBA 12/2017
1	Proteasome InhibitorsIBA 12/2017
1	Bortezomib (Velcade)FDA Link 12/2017
1	UbiquitinIBA 12/2017
1	ixazomibIBA 12/2017
1	P-selectin ligand proteinIBA 10/2017
1	AntibodiesIBA 10/2017
1	P-SelectinIBA 10/2017
1	E-SelectinIBA 10/2017
1	SelectinsIBA 10/2017
1	LigandsIBA 10/2017
1	benzothiazoleIBA 01/2017
1	Tubulin ModulatorsIBA 10/2016
1	ResveratrolIBA 10/2016
1	TubulinIBA 10/2016
1	B-Form DNA (B-DNA)IBA 11/2013
1	ElementsIBA 08/2012
1	TransducinIBA 11/2011
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2011
1	F-Box ProteinsIBA 11/2011

Therapy/Procedure

12	Therapeutics 01/2021 - 10/2010
3	Drug Therapy (Chemotherapy) 01/2019 - 07/2008
1	Precision Medicine 01/2022
1	Radiotherapy 01/2021
1	Oral Administration 01/2020
1	Intraventricular Infusions 01/2020